北京生物醫(yī)學(xué)工程

兩種計(jì)算正常成年人短時(shí)心率變異性方法的比較研究

Comparative study on the measurement of short-time heartrate variability using two methods in healthy adults

作者：李靜王步青王衛(wèi)東

單位：中國(guó)人民解放軍總醫(yī)院醫(yī)學(xué)工程與維修中心（北京100853）

分類號(hào)：R318.04

出版年·卷·期（頁碼）：2017·36·5（502-506）

摘要：

目的利用光電容積脈搏波法分析心率變異性，為通過心率變異性(heart rate variability,HRV)參數(shù)表征自主神經(jīng)系統(tǒng)的變化提供新的研究方法。方法對(duì)46個(gè)健康成年受試者分別同步采集自主呼吸狀態(tài)下的心電信號(hào)和光電容積脈搏波信號(hào)，利用二階差分極大值提取心電圖的RR間期，搜索脈搏波極大值提取脈搏波主波波峰間期PP，然后計(jì)算通用HRV參數(shù)SDNN、RMSSD和LF/HF，并利用回歸的統(tǒng)計(jì)學(xué)方法結(jié)合Bland-Altman隨機(jī)分析法對(duì)這兩種方法獲取的HRV結(jié)果進(jìn)行比較。結(jié)果兩種方法計(jì)算得到的心率變異性參數(shù)結(jié)果的Pearson相關(guān)系數(shù)分別為0.998、0.995和0.992，均顯著相關(guān)(P<0.01)， Bland-Altman分布圖也均在一致性區(qū)間內(nèi)，說明這兩種方法在計(jì)算心率變異性上具有一致性。結(jié)論利用光電容積脈搏波法分析心率變異具有可行性。

Objective To study the measurement of heart rate variability by using electrocardiogram (ECG) and photoplethysmography(PPG). Methods We analyzed heart rate variability (HRV) taken by ECG and photoplethysmography.After acquiring the synchronized ECG as well as the photoplethysmography on 46 healthy adults in their natural breathing state and extracting the RR intervals of ECG and PP intervals of PPG respectively,the time domain and frequency domain parameters of HRV were calculated. Results The correlation coefficients of the three short-time parameters in the two calculation methods were greater than 0.99 significantly,and the Bland-Altman scattered plot of the parameters were in the consistent band.The two methods had coherence in the calculation of heart rate variability. Conclusions It is feasible to analyze the heart rate variation with the pulse wave method.

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