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目的 研究雙向抑郁癥患者與健康人群腦部磁共振圖像在前額葉腦白質(zhì)區(qū)的紋理差異。方法 在抑郁癥患者組和健康對(duì)照組中隨機(jī)各選取8名志愿者，進(jìn)行相同的腦部磁共振掃描，選取左右額葉腦白質(zhì)作為研究對(duì)象，提取實(shí)驗(yàn)組和對(duì)照組樣本的紋理特征，使用最小分類誤差與最小平均相關(guān)系數(shù)法對(duì)紋理特征進(jìn)行篩選及分類比較研究。結(jié)果 通過(guò)比較原始數(shù)據(jù)分析(raw data analysis，RDA)、主成分分析(principal component analysis，PCA)、 線性判別分析(linear discriminant analysis，LDA)、非線性判別分析(nonlinear discriminant analysis，NDA)4種分類方法，發(fā)現(xiàn)LDA和NDA方法對(duì)樣本紋理分類正確率高于RDA和PCA分類方法。結(jié)論 抑郁癥患者與健康人群腦部磁共振圖像的前額葉腦白質(zhì)區(qū)紋理特征存在差異。

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