北京生物醫(yī)學(xué)工程

一種便攜式多部位超聲骨密度測量儀的研究

Research on a portable ultrasonic bone densitometer for multiple sites

作者：許楊陳焱焱丁增輝徐玉兵馬祖長孫怡寧

單位：中國科學(xué)院智能機(jī)械研究所（合肥 230031）中國科學(xué)技術(shù)大學(xué)自動化系（合肥 230026）

關(guān)鍵詞：骨密度; 定量超聲; 便攜式; 橈骨; 脛骨; 骨質(zhì)疏松

分類號：R318.6

出版年·卷·期（頁碼）：2018·37·2（193-196）

摘要：

Objective We developed a new ultrasound densitometer to estimate bone mineral density accurately at radius and tibia, and compared the values of ultrasound measurements obtained in a clinical study with gold standard measurement: dual-energy X-ray absorptiometry (DEXA) to determine the validity of the new device. Methods The probe was designed based on ultrasonic axial-transmission technology by using doubleemission and double-receiving mechanism. A temperature sensor was used to amend the results in the ultrasound measurements. Twenty five subjects aged 35. 5 years ± 11. 7 years were recruited for this study. The ultrasound parameters (SOSFAS-radius, SOSFAS-tibia) of each subject were measured in the distal 1/3 radius and middle tibia respectively, and bone mineral density (BMD) at the lumbar spine (the vertebral levels L2-L4) was measured. Pearson's correlation coefficient was used to assess the relationships between the two ultrasound parameters and BMD. Results The correlation coefficients of SOSFAS-radiusand SOSFAS-tibiawith BMD were r = 0. 68 (P<0. 001) , and r= 0. 77 (P<0. 001) , respectively. Conclusions The parameters measured by the new device and BMD measured by DXEA were significantly correlated. Moreover, the device was designed at low cost and portable, which enable the popularization of osteoporosis diagnosis and monitoring, to provide an effective means for the screening of osteoporosis in large population-based.

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