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Objective Aiming at the problem that the existing frequency response compensation algorithm for digital hearing aids in noisy environments can not meet the requirement of the deaf for intelligibility and comfort of digital hearing aids, we proposed the multi-channel frequency response compensation algorithm based on two-step noise reduction in this paper.Methods First, we calculate the prior signal-to-noise ratio and system gain of the common single-channel speech enhancement, and use the correlation between the previous and the subsequent speech frame to optimize the priori SNR estimation with the adaptive priori SNR smoothing factor so that two-step noise reduction is implemented.Then, the gammatone filter is used to perform nonuniform multi-subband decomposition on the enhanced speech, and interpolation is performed twice in each sub-band.Finally, the frequency response of each frequency band is compensated according to the hearing loss curve of the deaf.Results Experiments show that this algorithm can effectively remove the impact of noise on the frequency response compensation, protect the structure of the formant, obtain more information, compensate the missing speech energy of the patient, and meet the hearing requirement of people with hearing loss.Conclusions The proposed method can effectively improve the intelligibility and comfort of auditory perception of hearing impaired patients.