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彈簧圈栓塞治療腦動脈瘤的血流動力學(xué)數(shù)值模擬研究現(xiàn)狀

A review: hemodynamic numerical simulation of cerebral aneurysm with coil embolization

作者: 李蝶  程云章  王盛強 
單位:上海理工大學(xué)醫(yī)療器械與食品學(xué)院(上海 200093)<p>上海沃比醫(yī)療科技有限公司(上海 201138)</p>
關(guān)鍵詞: 腦動脈瘤;彈簧圈;血流動力學(xué);計算流體力學(xué);數(shù)值模擬 
分類號:R318.04; R651.1
出版年·卷·期(頁碼):2018·37·6(635-642)
摘要:

彈簧圈栓塞術(shù)是目前普遍應(yīng)用的腦動脈瘤治療手段, 近年來關(guān)于腦動脈瘤血流動力學(xué)數(shù)值模擬研究逐漸深入。基于醫(yī)學(xué)圖像的數(shù)值模擬在腦動脈瘤的診斷、治療方面具有很大的潛力。文章首先介紹了影響腦動脈瘤栓塞術(shù)的血流動力學(xué)參數(shù)、計算流體力學(xué)方法, 然后對比分析了多種彈簧圈栓塞腦動脈瘤的數(shù)值模擬方法。多數(shù)研究者采用了簡化的方法, 如采用牛頓血液模型、剛性或非剛性血管壁、定常流環(huán)境及彈簧圈的等效模擬等方法, 這些方法得出的結(jié)果與采用流固耦合方法、脈動流、非牛頓血流模型及真實彈簧圈模型得出的結(jié)果存在差異。最后對彈簧圈栓塞治療腦動脈瘤血流動力學(xué)研究進行了總結(jié)和展望。

Coil embolization is the most commonly used method in the treatment of cerebral aneurysm.In recent years, the hemodynamics research of cerebral aneurysm has been gradually deepened. CFD simulations based on medical images have great potential in the diagnosis and treatment of cerebral aneurysms.The article firstly introduces the hemodynamic parameters that affect cerebral aneurysm embolization and computational fluid dynamics methods, then compares the numerical simulation methods of coil embolized cerebral aneurysms. Most researchers adopt simplified methods, such as Newtonian blood model, rigid or nonrigid blood vessel wall, steady flow environment and equivalent simulation of coil. The results obtained by these methods are different from the results obtained by the fluid-solid coupling method, pulsatile flow, nonNewtonian flow model and real coil model. Finally, the conclusion and prospect of coil embolization in the treatment cerebral aneurysm hemodynamics are summarized.

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