北京生物醫(yī)學(xué)工程

便攜式生物阻抗相位角測量儀

Portable bio-impedance phase angle measuring instrument

作者：馬鴻斌田常正蔡希昌霍小林張廣浩

單位：北方工業(yè)大學(xué)（北京 100144）<p>中國科學(xué)院電工研究所（北京100190）</p>

關(guān)鍵詞：生物阻抗相位角；人體成分； AFE4300； STM32；鋰電池

分類號：R318.04，TN98

出版年·卷·期（頁碼）：2019·38·1（89-95）

摘要：

目的設(shè)計(jì)一臺(tái)便攜式的生物阻抗相位角測量儀，用于分析人體各身體成分及營養(yǎng)狀況。方法為提高測量儀測量精度和數(shù)據(jù)分析能力，采用八電極分段阻抗測量方法，通過計(jì)算即可得到身體分段的阻抗。采用TI公司生產(chǎn)的AFE4300高集成度前端方案，以提高其便攜性和測量精度。該測量儀主要分為6個(gè)部分，分別是AEF4300芯片集成前端、STM32單片機(jī)電路、有機(jī)發(fā)光二極管（organic light-emitting diode，OLED）顯示器、電池及電源電路、USB數(shù)據(jù)傳輸電路及Flash數(shù)據(jù)存儲(chǔ)器。其中，AFE4300集成前端實(shí)現(xiàn)電極的驅(qū)動(dòng)與測量、ADC轉(zhuǎn)換和IQ解調(diào)等功能；STM32 單片機(jī)用于控制整個(gè)測量儀；OLED顯示器進(jìn)行數(shù)據(jù)顯示；電池及電源電路通過低壓差線性穩(wěn)壓器（low dropout regulator，LDO）技術(shù)實(shí)現(xiàn)并采用鋰電池供電；USB數(shù)據(jù)傳輸電路實(shí)現(xiàn)數(shù)據(jù)的上傳和鋰電池的充電功能；Flash數(shù)據(jù)存儲(chǔ)器用于存儲(chǔ)測量數(shù)據(jù)和校準(zhǔn)數(shù)據(jù)。結(jié)果通過對人體阻抗RC三元件模型的測量驗(yàn)證，該測量儀在阻抗模測量和相位角測量方面的誤差分別低于2%和4%。通過對志愿者實(shí)測，測量時(shí)間約為30s，符合相關(guān)文獻(xiàn)數(shù)據(jù)。結(jié)論該測量儀的精度和測量速率都可以滿足實(shí)用化要求，具有一定的市場價(jià)值。

Objective To design a portable bio-impedance phase angle measurement system for the analysis of human body composition and nutritional status. Methods In order to improve the measurement accuracy and data analysis ability, the measuring instrument uses the eight-electrode segment impedance measurement method, through the calculation can get the impedance of body segment. To improve the portability and measurement accuracy, TI's AFE4300 highly integrated front-end program is used. The measuring instrument is divided into six parts, they are AEF4300 chip integrated front end, STM32 microcontroller circuit, OLED (organic light-emitting diode) display, battery and power supply circuit, USB data transmission circuit and flash data memory. Among them, AFE4300 integrated front-end is uesd to achieve the electrode drive and measurement, ADC conversion and IQ demodulation and other functions. STM32 MCU is used to control the whole measuring instrument, OLED is used to display the data, battery and power circuit supplied by lithium battery works according to the principle of LDO,USB data transmission circuit is used to achieve data upload and lithium battery charging function;flash data memory is used to store measurement data and calibration data. Results Through the measurement of the RC three component model of human body impedance, the error of the measuring instrument in impedance mode measurement and phase angle measurement is less than 2% and 4% respectively. Through the measurement of volunteers, the measurement time is about 30 seconds, basically consistent with the relevant literature data. Conclusions The above test proved that the accuracy of the measuring instrument and measurement rate can meet the practical requirements, so it has a certain market value.

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