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喉癌的發(fā)病率占頭頸部惡性腫瘤的第二位并有上升趨勢，手術(shù)后因喉組織缺損致喉呼吸、發(fā)音及吞咽等功能障礙，嚴(yán)重影響喉癌患者的生存率及生活質(zhì)量。將組織工程支架用于喉相關(guān)疾病的治療是較理想的方法之一，其中如何選擇合適的種子細(xì)胞將其賦予支架中是非常重要的環(huán)節(jié)。干細(xì)胞作為種子細(xì)胞用于軟骨修復(fù)已經(jīng)證實優(yōu)于分化的細(xì)胞如軟骨細(xì)胞等，本文從喉軟骨修復(fù)的國內(nèi)外研究現(xiàn)狀、干細(xì)胞的分類、干細(xì)胞修復(fù)軟骨組織的作用機(jī)制等方面進(jìn)行介紹，并分析了當(dāng)前干細(xì)胞的相關(guān)研究進(jìn)展對未來應(yīng)用于臨床的前景。

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