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目的 探索基于三維重建肺腫瘤的微波消融仿真方法,為個(gè)性化手術(shù)規(guī)劃模型提供理論基礎(chǔ)。方法 首先利用 Mimics 三維重建軟件將荷瘤兔 CT 圖像重建成三維數(shù)字化模型,同時(shí)在 COMSOL 仿真軟件中構(gòu)建了微波天線模型和理想化肺模型,組成微波消融仿真幾何模型。然后采用有限元仿真方法,固定消融功率為 30W,設(shè)置組織熱物性參數(shù)及邊界條件計(jì)算腫瘤組織和肺組織溫度場(chǎng)分布,分析得出合適的消融參數(shù)。結(jié)果 成功建立了 13. 63 mm×11. 31 mm 的橢球狀肺腫瘤的三維模型。基于電磁場(chǎng)與溫度場(chǎng)的計(jì)算,可以得到腫瘤溫度場(chǎng)和肺組織溫度場(chǎng)的分布。在使用消融功率 30 W / 消融時(shí)間 300 s時(shí),可以使其溫度場(chǎng)完全覆蓋兔肺腫瘤并預(yù)留出安全的消融邊界。結(jié)論 根據(jù)個(gè)性化腫瘤 CT 可成功建立其三維腫瘤模型,應(yīng)用于仿真研究之中可以從腫瘤組織和肺組織溫度場(chǎng)分布得到合適的消融參數(shù),該法對(duì)降低微波消融肺腫瘤手術(shù)難度?改善微波消融肺腫瘤手術(shù)效果有著重要意義。

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