北京生物醫(yī)學(xué)工程

基于移動(dòng)智能終端的單通道胎兒心電監(jiān)護(hù)系統(tǒng)

Design of single channel fetal ECG monitoring system based on mobile intelligent terminal

作者：朝暉安蒙蒙陳立鋒周斌鄭政

單位：上海理工大學(xué)生物醫(yī)學(xué)工程研究所（上海 200093） 東南大學(xué)生物科學(xué)與醫(yī)學(xué)工程學(xué)院（南京 210096） 通信作者：卜朝暉，副教授。E-mail: [email protected]

關(guān)鍵詞：胎兒心電提取；擴(kuò)展卡爾曼濾波；奇異值分解；移動(dòng)智能終端；Android

分類(lèi)號(hào)：R318.6

出版年·卷·期（頁(yè)碼）：2021·40·4（377-384）

摘要：

目的設(shè)計(jì)基于移動(dòng)智能終端的單通道胎兒心電監(jiān)護(hù)系統(tǒng)，以實(shí)現(xiàn)擴(kuò)展卡爾曼濾波(extended Kalman filtering，EKF)和奇異值分解（singular value decomposition，SVD）相結(jié)合的單通道胎兒心電提取算法，實(shí)時(shí)獲取高信噪比的胎兒心電信號(hào)，完成胎心監(jiān)護(hù)的遠(yuǎn)程移動(dòng)醫(yī)療。方法利用STM32單片機(jī)控制24位采樣芯片ADS1298，對(duì)單通道的孕婦腹部信號(hào)進(jìn)行采集，并將采集后的數(shù)據(jù)經(jīng)藍(lán)牙傳送給移動(dòng)智能終端，在基于Android的移動(dòng)智能終端上實(shí)現(xiàn)EKF和SVD相結(jié)合的單通道胎兒心電提取算法，完成對(duì)胎兒心電的實(shí)時(shí)提取、顯示、存儲(chǔ)與分析，計(jì)算心律變異率，實(shí)現(xiàn)對(duì)整個(gè)監(jiān)護(hù)系統(tǒng)進(jìn)行控制等功能。結(jié)果測(cè)試結(jié)果表明：該系統(tǒng)可從單通道孕婦腹部信號(hào)中準(zhǔn)確提取出胎兒心電信號(hào)，準(zhǔn)確度為95.60%，陽(yáng)性預(yù)測(cè)率為98.71%，系統(tǒng)工作穩(wěn)定，連續(xù)處理5個(gè)胎心周期的數(shù)據(jù)所花時(shí)間約為70 μs，小于一個(gè)母體心動(dòng)周期（約0.8 s）的時(shí)間，適于臨床對(duì)胎兒心電的實(shí)時(shí)監(jiān)護(hù)。結(jié)論該系統(tǒng)實(shí)時(shí)性強(qiáng)、準(zhǔn)確率高、工作穩(wěn)定、操作簡(jiǎn)單、便于攜帶，實(shí)現(xiàn)了對(duì)胎心監(jiān)護(hù)的可穿戴式遠(yuǎn)程移動(dòng)醫(yī)療，適合社區(qū)醫(yī)院和家庭使用。

Objective A single channel fetal ECG monitoring system based on mobile intelligent terminal is designed, and a single channel fetal ECG extraction algorithm combining extended Kalman filter (EKF) and singular value decomposition (SVD) is realized. The fetal ECG signal with high signal-to-noise ratio is obtained in real time, and the remote mobile medical treatment of fetal heart monitoring is realized. Methods Using STM32 single chip microcomputer to control 24 bit sampling chip ads1298, the single channel pregnant women's abdominal signal is collected, and the collected data is transmitted to the mobile intelligent terminal via Bluetooth. On the Android-based based mobile intelligent terminal, a single channel fetal ECG extraction algorithm based on the combination of EKF and SVD is realized, and the functions of real-time extraction, display, storage and analysis of fetal ECG, calculation of heart rate variability and control of the whole monitoring system are completed. Results The test results show that the system can accurately extract fetal ECG signals from single-channel pregnant women's abdominal signals, with an accuracy of 95.60% and a positive prediction rate of 98.71%. The system works stably, and it takes about 70μs to continuously process the data of 5 fetal cardiac cycles, which is less than the time of one maternal cardiac cycle (about 0.8s), which is suitable for clinical real-time monitoring of fetal ECG. Conclusions The system has strong real-time performance, high accuracy, stable work, simple operation and portability. It realizes wearable remote mobile medical care for fetal heart monitoring, and is suitable for community hospitals and families.

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