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目的 當(dāng)前關(guān)于脈診的血流動(dòng)力學(xué)建模研究集中于分析各種生理病理變化對(duì)脈象的影響，而忽略了切脈對(duì)橈動(dòng)脈血流的干預(yù)作用，所以無(wú)法從物理上解釋寸口脈與所主病癥的關(guān)系。本研究通過(guò)分析切脈對(duì)橈動(dòng)脈血流動(dòng)態(tài)的影響以探討寸口脈浮中沉脈位和所表征病癥的聯(lián)系。方法 本研究構(gòu)建了簡(jiǎn)單的橈動(dòng)脈血流動(dòng)力學(xué)模型，推導(dǎo)了血流特征量（包括寸口處的血流摩擦損失、橈動(dòng)脈血流動(dòng)態(tài)響應(yīng)的自然頻率和阻尼比等）隨切脈深度而變化的定量關(guān)系，以評(píng)估切脈對(duì)橈動(dòng)脈血流動(dòng)態(tài)的影響。結(jié)果 研究發(fā)現(xiàn)橈動(dòng)脈血流動(dòng)態(tài)響應(yīng)的自然頻率隨切脈深度的增加而增大但基本保持在之間。該變化范圍和正常人脈搏波的主要頻譜范圍高度重合，因此通過(guò)切脈至不同深度產(chǎn)生橈動(dòng)脈血流動(dòng)態(tài)響應(yīng)的頻率特性變化，可以與脈搏波頻譜中不同的頻率分量合拍共振，從而在寸口處捕捉到脈搏波中對(duì)應(yīng)于不同生理病理狀態(tài)的頻率成分。結(jié)論 本研究從切脈引起橈動(dòng)脈血流動(dòng)態(tài)響應(yīng)的自然頻率變化的角度，為寸口脈浮中沉脈位與不同病癥狀態(tài)的聯(lián)系提供了初步解釋。

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