北京生物醫(yī)學(xué)工程

3D打印在顱內(nèi)動脈瘤血管內(nèi)治療中的應(yīng)用

Application of 3D printing in endovascular treatment of intracranial aneurysms

作者：楊彥晨白斌程云章

單位：上海理工大學(xué)上海介入醫(yī)療器械工程技術(shù)研究中心 (上海 200093) 通信作者:程云章,教授。E-mail: [email protected]

關(guān)鍵詞： 3D打印;顱內(nèi)動脈瘤;血管內(nèi)治療;精準(zhǔn)度;材料

分類號：R318

出版年·卷·期（頁碼）：2021·40·6（642-646）

摘要：

隨著社會科技的發(fā)展與人們對于醫(yī)療領(lǐng)域的關(guān)注，顱內(nèi)動脈瘤愈發(fā)被大家關(guān)注，血管內(nèi)治療作為目前主流的治療方式，其介入裝置的部署狀態(tài)與效果是醫(yī)生關(guān)注的重點。3D打印技術(shù)作為一種新的成型技術(shù)，在醫(yī)療領(lǐng)域的應(yīng)用也已逐步成熟，為醫(yī)生可視化理解動脈瘤結(jié)構(gòu)與研究介入裝置治療后血流動力學(xué)環(huán)境做出了貢獻(xiàn)。本文論述了 3D打印的流程、時間、材料、工藝和精度，并結(jié)合實際案例說明了 3D打印技術(shù)在術(shù)前評估、改進(jìn)手術(shù)方案和提高患者滿意率上的作用。

With the development of social science and technology and peopleJ s attention to the medical field, intracranial aneurysms have been paid more and more attention. Endovascular therapy is the mainstream treatment at present, the deployment status and the effect of interventional devices are the focus of doctors' attention. As a new molding technology,3D printing technology has been gradually matured in the medical field, which contributes to the visual understanding of aneurysm structure and the study of hemodynamic environment after interventional treatment. This article discusses the process, cost time, materials, technique and accuracy of 3D printing, and combined with actual cases to illustrate the role of 3D printing technology in preoperative evaluation, improvement of operation plan and improvement of patient satisfaction rate.

參考文獻(xiàn)：

[1 ] Wisniewski K, Tomasik B, Bobeff EJ, et al. Predictors for ophthalmic segment aneurysms recanalization after coiling and flow diverter embolization in 6- and 12-month follow-up [ J]. Journal of Clinical Neuroscience,2019,68： 151-157.

[2 ] Zhu D, Yan Y,Zhao P ,et al. Safety and efficacy of flow diverter treatment for blood blister-like aneurysm: a systematic review and meta-analysis [ J]. World Neurosurgery ,2018,118:e79-e86.

[3 ] Gory B, Berge J, Bonafe A, et al. Flow diverters for intracranial aneurysms: the DIVERSION National Prospective Cohort Study [J], Stroke,2019,50( 12) :3471-3480.

[4 ] Corriveau M, Ahmed A, Dawkins D, et al. The effect of flow diverting stents on in vivo intrasaccular aneurysm pressure [J]. Journal of Clinical Neuroscience,2019,59:339—341.

[5 ] Briganti F, Napoli M, Leone G, et al. Treatment of intracranial aneurysms by flow diverter devices: long-term results from a single center [ J ]. European Journal of Radiology, 2014, 83 ( 9 ):1683-1690.

[6 ]馬磊，劉純，郭小梅，等.3D打印在復(fù)雜主動脈疾病個體化腔內(nèi)治療中的應(yīng)用價值[J].放射學(xué)實踐,2018,33 ( 9)： 903-906.

Ma L,Liu C, Guo XM, et al. The application of 3D printing in individualized strategy for endovascular aortic repair in complex aortic diseases[ J]. Radiologic Practice,2018,33(9) :903-906.

[7 ] Charoo NA,Ali SFB,Mohamed EM,et al. Selective laser sintering 3D printing—an overview of the technology and pharmaceutical applications [ J ] . Drug Development and Industrial Pharmacy, 2020,46(6) ：869-877.

[8 ] Lau I, Wong YH, Yeong CH, et al. Quantitative and qualitative comparison of low- and high-cost 3D-printed heart models [ J]. Quantitative Imaging in Medicine and Surgery, 2019, 9(1):107-114.

[9 ]趙春伶，賈少薇，李劍，等.基于3D打印多孔支架和植入體的結(jié)構(gòu)設(shè)計研究進(jìn)展[J].醫(yī)用生物力學(xué),2019,34(4):446-452.

Zhao CL, Jia SW, Li J, et al. Research progress in structural design of porous scaflblds and implants based on 3D printing [J]. Journal of Medical Biomechanics,2019,34(4):446-452.

[10]劉宇清，呂翱，黃繩躍，等.基于顱腦CTA 3D打印技術(shù)在顱內(nèi) 動脈瘤手術(shù)治療中的應(yīng)用[JL中國微侵襲神經(jīng)外科雜志.2016,21(6)：245-247.

Liu YQ, Lyu A, Huang SY, et al. Application of three dimensional printing technology based on CT angiography in the treatment of intracranial aneurysmf J]. Chinese Journal of Minimally Invasive Neurosurgery,2016,21 (6) :245—247.

[11 ] Wang JL, Yuan ZG, Qian GL, et al. 3D printing of intracranial aneurysm based on intracranial digital subtraction angiography and its clinical application [ J]. Medicine ( Baltimore) ,2018,97 (24):el1103.

[12]?Kim PS, Choi CH, Han IH, et al. Obtaining informed consent using patient specific 3D printing cerebral aneurysm model [ J]. Journal of Korean Neurosurgical Society,2019,62(4) :398-404.

[13]?Kono K,Shintani A, Okada H, et al. Preoperative simulations of endovascular treatment for a cerebral aneurysm using a patientspecific vascular silicone model [ J ]. Neurologia Medico- chirurgica,2013,53(5):347-351.

[14]?Xu L, Zhao B, Liu X, et al. Computational methods applied to analyze the hemodynamic effects of flow-diverter devices in the treatment of cerebral aneurysms: current status and future directions [ J ]. Medicine in Novel Technology and Devices, 2019,3:100018.

[15]?Usmani AY, Muralidhar K. Flow in an intracranial aneurysm model: effect of parent artery orientation [ J ]. Journal of Visualization,2018,21(5):795-818.

[16]?Chivukula VK,Levitt MR,Clark A,et al. Reconstructing patientspecific cerebral aneurysm vasculature for in vitro investigations and treatment efficacy assessments [ J ]. Journal of Clinical Neuroscience ,2019,61:153-159.

[17]?Nagassa RG, McMenamin PG, Adams JW, et al. Advanced 3D printed model of middle cerebral artery aneurysms for neurasurgery simulation [ J]. 3D Printing in Medicine, 2019, 5 (1):11-

[18]?Zhou G,Liu W,Zhang Y,et al. Application of three-dimensional printing in interventional medicine [ J] . Journal of Interventional Medicine,2020,3(l)：l-16.

[19]?Kang Y, Yu LH, Xu T, et al. Three-dimensional printing technology for treatment of intracranial aneurysm [ J]. Chinese Neurosurgical Journal,2016,2(3) : 125-134.

[20]?Kaneko N, Mashiko T, Namba K, et al. A patient-specific intracranial aneurysm model with endothelial lining: a novel in vitro approach to bridge the gap between biology and flow dynamics [ J]. Journal of Neurointerventional Surgery, 2018,10 (3):306-309.

[21]?孫振軍.3D打印技術(shù)在零件制造中精度及質(zhì)量控制方法研究 [J].山東工業(yè)技術(shù),2019(5):65.

[22]?Anderson JR, Thompson WL, Alkattan AK, et al. Three- dimensional printing of anatomically accurate, patient specific intracranial aneurysm models [J]. Journal of N eurointerventional Surgery,2016,8(5):517-520.

[23]?譚衍，邊遠(yuǎn)，陸弘盈，等.3D打印技術(shù)在顱內(nèi)動脈瘤介入栓塞治療中的應(yīng)用[J].中國醫(yī)學(xué)裝備,2017,14(12):64-67.

Tan Y, Bian Y, Lu HY, et al. The application of 3D printing technique in treatment of interventional embolization of intracranial aneurysm [ J ]. China Medical Equipment, 2017, 14 (12):64-67.

[24]?Vakharia VN, Vakharia NN, Hill CS. Review of 3 — dimensional printing on cranial neurosurgery simulation training [ J]. World Neurosurgery ,2016,88:188-198.

[25]?Xu Y,Tian W, Wei Z,et al. Microcatheter shaping using three- dimensional printed models for?intracranial aneurysm coiling[ J]. Journal of Neurointerventional Surgery,2020,12 (3) :308-310.

[26 ] Ishibashi T, Takao H, Suzuki T, et al. Tailor-made shaping of microcatheters using three-dimensional printed vessel models for endovascular coil embolization [ J]. Computers in Biology and Medicine,2016,77(C) :59-63.

[27 ] Kono K, Shintani A, Okada H, et al. Preoperative simulations of endovascular treatment for a cerebral aneurysm using a patientspecific vascular silicone model [ J ]. Neurologia Medico- chirurgica ,2013,53(5) :347—351.

[28]?康崟.3D打印技術(shù)在顱內(nèi)動脈瘤外科治療中的應(yīng)用研究 [D ].福州:福建醫(yī)科大學(xué),2016 :9-19,

Kang Y. Three-dimensional printing technology for treatment of intracranial aneurysms [ D ]. Fuzhou: Fujian Medical University, 2016:9-19.

[29]?Mashiko T, Otani K, Kawano R, et al. Development of three- dimensional hollow elastic model for cerebral aneurysm clipping simulation enabling rapid and low cost prototyping [ J]. World Neurosurgery,2015,83(3):351—361.

劉子燕，王榮耀,李艷明，等. 3D打印技術(shù)在顱內(nèi)動脈瘤介入栓塞術(shù)中的應(yīng)用[J].中外醫(yī)學(xué)研究,2017,15 (29):71-73, Liu ZY, Wang RY, Li YM, et al. Application of 3D printing in embolization of intracranial aneurysm embolization [ J ] . Chinese and Foreign Medical Research,2017,15(29):71—73

服務(wù)與反饋：

【文章下載】【加入收藏】

提示：您還未登錄，請登錄！點此登錄

51黑料吃瓜在线观看,51黑料官网|51黑料捷克街头搭讪_51黑料入口最新视频