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癲癇外科結構磁共振常見分析方法研究進展

Common analysis methods for structural MRI in epilepsy surgery

作者: 莫嘉杰  張建國  胡文瀚  張凱  
單位:首都醫(yī)科大學附屬北京天壇醫(yī)院神經(jīng)外科(北京 100070) <p>首都醫(yī)科大學北京市神經(jīng)外科研究所(北京 100070)</p> <p>通信作者:張凱。E-mail:[email protected]</p> <p>&nbsp;</p>
關鍵詞: 神經(jīng)影像;計算模型;統(tǒng)計分析;多重校正  
分類號:R318.04 <p>&nbsp;</p>
出版年·卷·期(頁碼):2022·41·1(97-103)
摘要:

結構磁共振(magnetic resonance imaging,MRI)對癲癇的診治至關重要,尤其是考慮行癲癇外科治療時。但癲癇外科部分常見病理類型(如皮質發(fā)育不良、海馬硬化)在常規(guī)閱片中表現(xiàn)隱蔽,給臨床工作帶來了巨大挑戰(zhàn)。因此,結合利用神經(jīng)影像后處理及統(tǒng)計分析方法,對影像數(shù)據(jù)進行分析、建模和解釋,進一步挖掘其量化識別和分析致癇灶的價值,將有利于增加其臨床指導價值。本文將針對目前癲癇外科結構磁共振常用的分析方法、計算模型和統(tǒng)計應用的研究進展進行綜述。

 

Structural magnetic resonance imaging( sMRI) is of fundamental important to the diagnosis and treatment of epilepsy, particularly when surgery is being considered. However, some common pathological types of epilepsy surgery ( such as focal cortical dysplasia, hippocampal sclerosis) are subtle in conventionally visual interpretation, which brings great challenges to presurgical workup. Therefore, the neuroimaging data analysis, modelling and interpretation using post-processing and statistical analysis methods will help to quantitatively identify and analyse the epileptogenic focus as well as increase its clinical value. The present article will introduce the analysis methods, calculation models and statistical applications of MRI in epilepsy surgery.

 

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