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生物組織收縮在微波消融術(shù)中的研究進(jìn)展

Research progress of biological tissue shrinkage in microwave thermal ablation

作者: 買(mǎi)欣  南群  胡昊  田甄 
單位:北京工業(yè)大學(xué)環(huán)境與生命學(xué)部生命科學(xué)與化學(xué)學(xué)院(北京 &nbsp;100124)<br />通信作者:南群,教授。E-mail: nanqun@ bjut. edu. cn
關(guān)鍵詞: 腫瘤;微波消融;生物組織收縮;體外實(shí)驗(yàn);收縮模型 
分類(lèi)號(hào):R318.04
出版年·卷·期(頁(yè)碼):2023·42·1(94-99)
摘要:

微波消融治療技術(shù)具有微創(chuàng)、操作簡(jiǎn)便、熱效率高、患者耐受性好等優(yōu)點(diǎn),目前已經(jīng)成為治療腫瘤的重要手段。在微波消融過(guò)程中,不同生物組織受熱會(huì)發(fā)生不同程度的收縮,影響到消融區(qū)域的大小。而生物組織消融區(qū)域?qū)υu(píng)估治療療效至關(guān)重要,同時(shí)在提高臨床治療的有效性和安全性方面也起著重要作用。因此,研究生物組織收縮具有重要的臨床意義。本文首先分析了生物組織收縮的理論基礎(chǔ);其次對(duì)現(xiàn)有生物組織收縮的體外實(shí)驗(yàn)和數(shù)學(xué)模型進(jìn)行了評(píng)估和分析;最后總結(jié)了目前相關(guān)生物組織收縮研究中所存在的局限性,并提出了今后的研究方向。

Microwave ablation(MWA) therapy technology has the advantages of minimal invasiveness, simple operation, high thermal efficiency, and good patient tolerance. It has become an important method for the treatment of tumors. During the microwave ablation process, different biological tissues will shrink to different degrees when heated, which affects the size of the ablation area. The area of biological tissue ablation is very important for evaluating the efficacy of treatment, and it also plays an important role in improving the effectiveness and safety of clinical treatment. Therefore, studying the shrinkage of biological tissues has important clinical significance. This article first analyzes the theoretical basis of biological tissue shrinkage; secondly, it evaluates and analyzes the in vitro experiments and mathematical models of the existing biological tissue shrinkage; finally, it summarizes the limitations of the current related biological tissue shrinkage research and proposes future researh directions.

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