北京生物醫(yī)學(xué)工程

糖尿病患者“寸、關(guān)、尺”脈搏壓力波形的頻譜分析

Frequency spectrum analysis on pressure pulse wave of diabetes mellitus at Cun, Guan and Chi based on TCM

作者：李本森盧意成龔文波繆馥星

單位：寧波大學(xué)沖擊與安全工程教育部重點(diǎn)實(shí)驗(yàn)室(浙江寧波 315211)<br />寧波市中醫(yī)醫(yī)院王暉工作室(浙江寧波 315000)<br />通信作者：繆馥星，教授。E-mail: [email protected]

關(guān)鍵詞：脈搏壓力信號(hào)；頻譜分析；糖尿病癥；寸、關(guān)、尺三點(diǎn)脈搏壓力信號(hào)

分類號(hào)：R318.04

出版年·卷·期（頁(yè)碼）：2023·42·2（117-123）

摘要：

目的對(duì)糖尿病受試者的脈搏信號(hào)進(jìn)行頻域分析，研究糖尿病受試者脈搏波形在頻域范圍內(nèi)的特性，探討從頻域特征判斷糖尿病的可能性。方法應(yīng)用三通道中醫(yī)脈象儀，通過(guò)中醫(yī)切脈定位寸、關(guān)、尺，采集糖尿病受試者和健康受試者的脈象信息，對(duì)采集的脈象信息進(jìn)行頻域分析，并對(duì)功率譜密度的峰值進(jìn)行指數(shù)擬合、統(tǒng)計(jì)糖尿病受試者與健康受試者的頻域分布范圍、峰值個(gè)數(shù)，以及低次諧波偏差、高次諧波偏差、總諧波偏差。結(jié)果通過(guò)對(duì)數(shù)據(jù)的統(tǒng)計(jì)分析、與健康受試者的數(shù)據(jù)對(duì)比發(fā)現(xiàn)：糖尿病癥受試者的脈搏波頻率分布范圍較大，諧波峰值的指數(shù)衰減特征與健康受試者具有很大不同，同一受試者寸、關(guān)、尺同樣具有很大不同，且糖尿病癥受試者的第一主峰的分布頻率要比健康受試者的高。結(jié)論糖尿病癥受試者與健康受試者頻率分布范圍不同，高次諧波偏差以及寸位置的第一主峰頻率可以作為區(qū)分健康受試者以及糖尿病癥受試者的特征參數(shù)。臨床測(cè)量驗(yàn)證了寸、關(guān)、尺脈搏波信號(hào)的不同，也恰佐證了中醫(yī)脈診過(guò)程中，區(qū)別寸、關(guān)、尺脈象的指代意義，并綜合診斷的中醫(yī)實(shí)踐。本文的初步研究結(jié)果將對(duì)進(jìn)一步認(rèn)識(shí)糖尿病癥及其中醫(yī)臨床脈診的科學(xué)化奠定基礎(chǔ)。

Objective The pulse signals of diabetic subjects were analyzed in the frequency domain to study the characteristics of their pulse waveforms in the frequency domain and to explore the possibility of judging diabetes from the characteristics of the frequency domain. Methods The pulse signals of diabetic subjects and the pulse wave characteristics of clinical pulses of diabetic subjects were collected by using the three-channel traditional Chinese medicine pulse instrument, and the collected pulse signals were analyzed in the frequency domain, and the power spectrum density was fitted and statistically analyzed. The frequency domain distribution range, peak number, low-order harmonic deviation（LHD）, high-order harmonic deviation（HHD）, and total harmonic deviation（THD） of diabetic subjects and healthy subjects were counted. Results Through statistical analysis of the data and compared with the data of healthy subjects, it is found that the pulse wave frequency distribution range of diabetic subjects is larger, the exponential attenuation characteristics of the harmonic peak are very different from those of healthy subjects, the Cun, Guan, and Chi for the same subjects are also very different, and the distribution frequency of the first main peak of diabetic subjects is higher than that of healthy subjects. Conclusions The frequency distribution range of diabetic subjects is different from that of healthy subjects. The HHD and the frequency of the first main peak at Cun can be used as characteristic parameters to distinguish healthy subjects from diabetic subjects. The clinical measurement also verifies the difference in pulse wave signals at Cun, Guan, and Chi by the clinical measurement. It also proved that traditional Chinese medicine practice has scientific property by distinguishing the referential meaning of Cun, Guan, and Chi pulses in the process of pulse diagnosis. The present research results will lay the foundation for further understanding of diabetes and its Chinese medicine clinical pulse diagnosis.

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