北京生物醫(yī)學(xué)工程

凝集素ConA對(duì)紅細(xì)胞小變形及其在C＝0軌道取向的影響

The Effects of Agglutinin ConA on Erytherocyte small Deformation and its Orientation in Orbit C=0

作者：趙玉衡; 賈麗玫; 張曉華; 文宗曜;

單位：北京醫(yī)科大學(xué)物理教研室;

關(guān)鍵詞：激光衍射法; 紅細(xì)胞變形; 紅細(xì)胞取向;

分類號(hào)：

出版年·卷·期（頁碼）：1994·1·3（170-173）

摘要：

作者用激光衍射法研究了凝集素ＣｏｎＡ對(duì)紅細(xì)胞在低粘度低剪切率流場(chǎng)中小變形及其在Ｃ＝０軌道取向的影響。結(jié)果表明，在各種低剪切率γ下均有ＣｏｎＡ對(duì)紅細(xì)胞作用的量越大，紅細(xì)胞變形指數(shù)ＤＩ和取向指數(shù)ＯＩ就越小。這可能是由于ＣｏｎＡ與紅細(xì)胞膜上的受體結(jié)合，改變了細(xì)胞膜的成分、紅細(xì)胞膜剛性增強(qiáng)、粘彈性下降的結(jié)果。

The effects of agglutinin ConA on erytherocyte small deformation and its orientation in orbit C=0 in the low shear flow field of low viscosity were studied by means of ektacytometry.The results show that at any low shear rate γ,the more the effect of ConA on erytherocyte,the smaller the erytherocyte deformation index DI and orientation index OI.It might due to the combination of ConA and the receptor on the erytherocyte membrane,which result in the increasing of membrane rigidity and decreasing of membrane ...

參考文獻(xiàn)：

中國(guó)期刊全文數(shù)據(jù)庫共找到 1 條

[1]	董群,蘇雅嫻,李田勛,文宗耀. 凝集素及其受體相互作用對(duì)人紅細(xì)胞變形性的影響[J]. 細(xì)胞生物學(xué)雜志, 1992,(03) .

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