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一種基于多數(shù)據(jù)源融合的酵母蛋白質(zhì)相互作用預(yù)測方法

An Approach for Predicting Yeast Protein-Protein Interaction Network by Merging Multiple Data Sources

作者: 楊曉飛  鄭浩然  韓思遠  侯輝超  張寬 
單位:中國科學(xué)技術(shù)大學(xué)計算機科學(xué)技術(shù)系,合肥,230027
關(guān)鍵詞: 蛋白質(zhì)相互作用      多數(shù)據(jù)源      Logistic回歸      信號通路   
分類號:
出版年·卷·期(頁碼):2009·28·4(373-377)
摘要:

蛋白質(zhì)-蛋白質(zhì)相互作用在生命活動中起著重要的作用.本文通過整合多個數(shù)據(jù)源,采用Logistic回歸模型,對模式生物酵母所有的蛋白質(zhì)之間相互作用進行了計算預(yù)測,得到了一個酵母蛋白質(zhì)相互作用的加權(quán)網(wǎng)絡(luò),結(jié)果分析表明本文得到的蛋白質(zhì)相互作用網(wǎng)絡(luò)有較高的可靠性.

參考文獻:

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