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ICU中發(fā)生急性低血壓的預(yù)測方法研究進(jìn)展

The Research Progress of Forecasting Approaches for Acute Hypotension Occurring in ICU

作者: 賴麗娟  吳效明 
單位:華南理工大學(xué)生物醫(yī)學(xué)工程系(廣州510006)
關(guān)鍵詞: 急性低血壓;ICU;預(yù)測方法;動脈壓;特征選取 
分類號:
出版年·卷·期(頁碼):2010·29·5(538-542)
摘要:

在ICU監(jiān)護(hù)中,急性低血壓的發(fā)生可能引起嚴(yán)重的后果,甚至威脅患者的生命安全,如何檢測和提前預(yù)報急性低血壓發(fā)生已成為醫(yī)學(xué)界必須重視的臨床問題。近年來,醫(yī)療監(jiān)護(hù)技術(shù)和信號分析處理方法的迅速發(fā)展,促進(jìn)了對急性低血壓發(fā)生的預(yù)測方法的相關(guān)研究,研究內(nèi)容主要側(cè)重于兩個方面:一是通過研究與可能發(fā)生急性低血壓相關(guān)的生命體征參數(shù),發(fā)現(xiàn)動脈壓、心率及血氧飽和度等可以作為有效的指標(biāo)參數(shù);二是研究這些參數(shù)的變化趨勢,通過一定的時間窗和閾值判斷,可達(dá)到提前1小時預(yù)測急性低血壓的發(fā)生。將數(shù)字信號處理技術(shù)和臨床監(jiān)護(hù)參數(shù)相結(jié)合,是實(shí)現(xiàn)智能化監(jiān)護(hù)技術(shù)發(fā)展的方向,在繼續(xù)豐富監(jiān)護(hù)數(shù)據(jù)庫的基礎(chǔ)上,研究者們正致力于應(yīng)用醫(yī)學(xué)信息學(xué)方法認(rèn)識急性低血壓發(fā)生的規(guī)律,尋求提前預(yù)測急性低血壓發(fā)生的方法,進(jìn)而設(shè)計智能化預(yù)測軟件。以上研究有利于實(shí)現(xiàn)急性低血壓提前預(yù)測,提前干預(yù),大大降低搶救風(fēng)險,具有重大的臨床研究應(yīng)用價值。

The occurrence of acute hypotensive episode (AHE) in intensive care units can result in grave consequences and endanger the patient lives. How to detect and predict acute hypotensive episode in advance has become a clinical problem which is highly paid attention to by the medical world. In recent years, with the rapid development of the medical monitoring technology and signal analysis and processing methods, promoting a comprehensive study of forecasting approaches for acute hypotensive episode, the study mainly focuses on two aspects: one is the research of the vital signs that is likely related to the occurrence of acute hypotensive episode, showing that arterial blood pressure, heart rate and oxygen saturation , etc. can be acted as effective indicators. The other is to study the trend of changes in these vital signs, which would achieve forecasting acute hypotensive episode up to an hour in advance by defining a certain forecast window and the diagnostic threshold. It illustrates that integration of digitized signal processing technique with clinical monitoring parameters is the development direction for realizing intelligent monitoring technology. On the basis of continuing to enrich the database for monitoring, person concerned are committed to recognize the onset regularity of acute hypotension, looking for the approach that might forecast acute hypotensive episodes ahead of time and designing the intelligent forecast software. The study of this approach is beneficial to early prediction of acute hypotension and intervention, which would significantly reduce the death risk of patients and is of great value to clinical application.

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