北京生物醫(yī)學(xué)工程

定量超聲骨質(zhì)疏松檢測系統(tǒng)的研究與設(shè)計(jì)

A Quantitative Ultrasound Testing System for the Diagnosis of Osteoporosis

作者：王培勇楊良策

單位：清華大學(xué)體育部（北京100084）

分類號：

出版年·卷·期（頁碼）：2011·30·1（67-72）

摘要：

設(shè)計(jì)開發(fā)一套定量超聲骨質(zhì)疏松檢測系統(tǒng)，通過測量人體跟骨的超聲傳播速度（sound of speed，SOS）和超聲帶寬衰減系數(shù)（broadband ultrasound attenuation，BUA），全面評價(jià)骨質(zhì)疏松的狀況，為骨質(zhì)疏松的早期診斷和骨折的預(yù)防提供科學(xué)依據(jù)。定量超聲骨質(zhì)疏松檢測系統(tǒng)硬件電路采用89c52單片機(jī)平臺開發(fā)，實(shí)現(xiàn)超聲信號的發(fā)射與接收、數(shù)據(jù)的高速采集與通信、步進(jìn)電機(jī)的驅(qū)動與控制等功能；系統(tǒng)軟件采用Visual C#和Matlab混合編程技術(shù)開發(fā)，完成用戶添加與管理、超聲數(shù)據(jù)采集與處理、檢測結(jié)果存儲與打印等功能。與Osteosys公司的SONOST-3000超聲骨質(zhì)疏松檢測儀的比較研究結(jié)果顯示，本文中研制的定量超聲系統(tǒng)對骨質(zhì)疏松的檢測準(zhǔn)確，達(dá)到了設(shè)計(jì)要求，具有良好的應(yīng)用前景。

In order to diagnose the osteoporosis, a quantitative ultrasound system (QUS) for estimating the osteoporosis status was designed in this paper. By measuring the sound of speed (SOS) and broadband ultrasound attenuation (BUA) in calcaneus, this system can evaluate the osteoporosis status which provides a scientific basis for the early diagnosis of osteoporosis and even the prevention of bone fracture. The hardware circuits of QUS were developed on the 89c52 MCU platform, which realized the functions of ultrasound transmitting and receiving, high-speed data acquisition and communication, and stepper motor driving. The software of this system was developed by Visual C# and Matlab, which realized the functions of user management, ultrasound data acquisition and analysis, detection results storage and printout. Finally, a comparison experimental investigation was compared with SONOST-3000. The results showed that the detection precision of osteoporosis status was comparatively accurate, and the performance of this system meet the expected requirements.

參考文獻(xiàn)：

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