北京生物醫(yī)學(xué)工程

與人體血液需求量自適應(yīng)的血泵流量控制算法

Algorithm for Controlling Blood Pump Flow Rate Adaptively with Requirement of Human Body

作者：陳寧寧谷凱云軒艷嬌常宇

單位：北京工業(yè)大學(xué)生命科學(xué)與生物工程學(xué)院（北京100124）

關(guān)鍵詞：血泵；心率；流量；心輸出量

分類號(hào)：

出版年·卷·期（頁(yè)碼）：2011·30·1（89-91）

摘要：

目的為了使血泵驅(qū)動(dòng)器能夠根據(jù)患者的生理需求調(diào)節(jié)血泵輸出，提出基于心率的自適應(yīng)血泵控制算法，該算法得出的算法流量能隨著生理需求而變化。方法基于心率與心輸出量之間的關(guān)系，將血泵輸出流量設(shè)計(jì)成為心率的函數(shù)，根據(jù)文獻(xiàn)中提供的正常人體心率與心輸出量的數(shù)據(jù)，利用最小二乘法求得算法中的常量系數(shù)。為驗(yàn)證算法的準(zhǔn)確性，計(jì)算出根據(jù)算法所得到的血泵輸出流量與正常人體自然心臟心輸出量之間的最大誤差和相關(guān)系數(shù)。結(jié)果當(dāng)心率為75次/min時(shí)，根據(jù)上述算法得到的流量能達(dá)到5.01L/min；在50~120次/min心率范圍內(nèi)，算法中流量會(huì)隨著心率的提高而增大；算法流量與自然心臟心輸出量的相對(duì)誤差為1%，相關(guān)系數(shù)為0.997。結(jié)論以上結(jié)果表明，該算法可以根據(jù)受試者的血液需求量自動(dòng)調(diào)整血泵工作狀態(tài)。

Objective In order to regulate the blood pump responsing to the demand of patient’s cardio output, we proposed an adaptive blood pump control algorithm based on heart rate, so that the blood flow derived from the algorithm varies with the physiological needs. Methods Based on the relationship between heart rate and cardiac output, the algorithm was designed as a function of the heart rate. According to the data of heart rate and cardiac output derived from literatures, the constant coefficients were obtained through the least squares algorithm. To verify the accuracy of the algorithm, we calculated the maximum error and the correlation coefficient between the pump flow and cardiac output. Results With the algorithm,, the blood pump flow rate was 5.01L/min when heart rate of 75 beats/min, and the blood pump flow rate gradually became larger with the increase of heart rate within heart rate range from 50 to 120 times / min. The relative error between blood pump flow rate obtained from algorithm and cardiac output was 1%. Conclusion These results suggest that the algorithm for controlling blood pump flow rate regulate the pump in response to the demand of patient’s cardio output.

參考文獻(xiàn)：

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