北京生物醫(yī)學(xué)工程

一種可變系數(shù)的對(duì)數(shù)腦血管減影算法研究

Logarithmic subtraction algorithm of variable coefficient on cerebral blood vessels

作者：歐陽(yáng)麗蓉鄧振生嚴(yán)昂

單位：中南大學(xué)地球科學(xué)與信息物理學(xué)院（長(zhǎng)沙 410083）

關(guān)鍵詞：數(shù)字減影血管造影；可變系數(shù)；對(duì)數(shù)變換

分類號(hào)：

出版年·卷·期（頁(yè)碼）：2012·31·1（36-39）

摘要：

目的針對(duì)數(shù)字減影血管造影（digital subtraction angiography，DSA）血管圖像中非血管結(jié)構(gòu)難以完全去除，嚴(yán)重干擾對(duì)血管分析與診斷的問(wèn)題，本文尋求一種適用于腦血管DSA圖像的減影方法。方法根據(jù)X射線在人體組織中的吸收特性，提出一種可變系數(shù)的對(duì)數(shù)減影算法。該算法首先對(duì)造影前后的圖像分別進(jìn)行對(duì)數(shù)變換再相減，然后設(shè)計(jì)一個(gè)自適應(yīng)的擴(kuò)大系數(shù)，將對(duì)數(shù)減影后的圖像進(jìn)行灰度動(dòng)態(tài)范圍的擴(kuò)大。結(jié)果對(duì)源自臨床的一個(gè)實(shí)際造影圖像（蒙片和盈片）分別采用直接減影、一般的對(duì)數(shù)減影和本文的對(duì)數(shù)減影算法進(jìn)行處理，三種方法中本文算法獲得的圖像非血管結(jié)構(gòu)較少，對(duì)比度強(qiáng)。結(jié)論實(shí)驗(yàn)結(jié)果證明，可變系數(shù)對(duì)數(shù)減影算法能有效消除或降低背景噪聲，獲得血管灰度一致、對(duì)比度較強(qiáng)的血管圖像。

Objective Since the non-vascular structures can hardly be fully expelled from the blood vessels in the image of digital subtraction angiography(DSA)，which seriously interferes the analysis and diagnosis of blood vessels，this study looks for a subtraction method suitable for cerebral blood vessels from DSA. Methods According to the absorbing features of X-ray in human bodies，a logarithmic subtraction algorithm of variable coefficient was proposed. Logarithmic transformation was carried on the images of before- and after- angiography respectively，which were then subtracted. Then，a self-adaptive expanded coefficient was used to expand the range of the gray level of the subtraction image. Results Direct subtraction，ordinary logarithmic subtraction and the proposed method were performed on the clinical angiography images respectively in this paper. It showed that the proposed method could obtain images with less non-vascular structures and better contrast than the other two methods. Conclusions The logarithmic subtraction algorithm of variable coefficient might effectively eliminate or decrease background noises，which was helpful to obtain blood vessel images with uniform gray levels and good contrast.

參考文獻(xiàn)：

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