|
您當前的位置：電子期刊欄目→論著>>正文 |
|
基于單導腦電的數(shù)字化新生兒腦功能監(jiān)護儀的研制 Development of digitalized neonatal cerebral function monitor based on single-lead electroencephalography signal |
| 作者： 彭誠 丁海艷 楊寶爵 葉大田 |
| 單位：清華大學深圳研究生院(深圳518055) |
| 關鍵詞： 腦功能監(jiān)護；單導腦電；振幅整合腦電圖；嵌入式系統(tǒng) |
| 分類號： |
| 出版年·卷·期（頁碼）：2012·31·5（494-500） |
| 摘要： |
|
目的 新生兒腦功能監(jiān)護儀大多基于單導腦電設計以適于長時監(jiān)測。現(xiàn)有的新生兒腦功能監(jiān)護儀多通過模擬電路以獲取振幅整合腦電圖(amplitude-integrated EEG，aEEG)，其體積龐大，價格昂貴，缺少自動分析，在國內應用較少。為降低成本及提高便攜性，本文設計了數(shù)字化新生兒腦功能監(jiān)護儀。方法 設計包含電極-頭皮阻抗檢測模塊的前置腦電放大電路以采集單導腦電信號，利用基于OMAP-L137的雙處理器嵌入式開發(fā)板實時計算和顯示單導腦電的線性指標aEEG和非線性指標樣本熵(sample entropy，SampEn)，并設計實現(xiàn)用戶界面控制和病案數(shù)據(jù)管理。結果 本文設計的監(jiān)護儀能夠實時監(jiān)控新生兒單導腦電的線性指標aEEG和非線性指標SampEn，實現(xiàn)對新生兒腦功能發(fā)育及腦損傷的客觀、量化的評價。結論 該監(jiān)護儀提取的aEEG與現(xiàn)有設備具有較好的一致性，腦電的SampEn為新生兒腦功能判定提供了新的可靠判據(jù)，能夠更全面地反映新生兒腦功能狀況。 |
|
Objective Most of neonatal cerebral function monitors are designed based on single-lead electroencephalography (EEG) for long-time monitoring. The existing neonatal cerebral function monitors acquire the amplitude-integrated EEG (aEEG) with analog circuits, which are heavy, expensive, and seldom used in China. To improve the portability and reduce the cost of the instrument, a digitalized neonatal cerebral function monitor is developed. Methods The single-lead EEG was acquired by an EEG amplifier module with impedance detecting function. An embedded system based on dual-core embedded processer OMAP-L137 was designed to carry out the real-time computation and display of aEEG and sample entropy (SampEn), to realize the user interface control and patient information management. Results This neonatal cerebral function monitor detected aEEG and SampEn simultaneously, and then provided an objective and quantitative evaluation on neonatal cerebral function. Conclusions The aEEG acquired by the digitalized neonatal cerebral function monitor is in accord with the results of existing equipments. SampEn is a new and reliable criterion of EEG and the monitor presents neonatal cerebral function more comprehensively. |
| 參考文獻： |
|
［1］Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial ［J］. Lancet, 2005, 365(9460): 663-670. ［2］張丹丹, 丁海艷, 劉云峰, 等. 振幅整合腦電圖的實現(xiàn)及其在新生兒腦功能監(jiān)護中的應用前景 ［J］. 中國醫(yī)療器械信息, 2008, 1(3):43-47. |
| 服務與反饋： |
| 【文章下載】【加入收藏】 |
| 提示：您還未登錄，請登錄！點此登錄 |
|
|||||||||||||||||
|
|||||||||||||||||
|
|
地址：北京安定門外安貞醫(yī)院內北京生物醫(yī)學工程編輯部 電話：010-64456508 傳真：010-64456661 電子郵箱：[email protected] |