北京生物醫(yī)學(xué)工程

改進的檢測TWA的相關(guān)分析法

LI Tiantian,ZHAO Jie,LI Fei,GUO Hui

作者：李田田趙捷李斐郭慧

單位：山東師范大學(xué)物理與電子科學(xué)學(xué)院(濟南250014)

分類號：

出版年·卷·期（頁碼）：2012·31·6（570-573）

摘要：

目的T波交替(T wave alternans,TWA)可獨立預(yù)測室性心律失常與猝死，但傳統(tǒng)的檢測方法實時性較差。為實現(xiàn)短時T波交替的檢測，提高實時性，本文利用改進的方法檢測心電信號，為TWA信號的檢測分析提供新手段。方法改進傳統(tǒng)相關(guān)分析法中對齊時的模板及計算交替指數(shù)時的模板，待檢測信號取自MIT-BIH和ST-T數(shù)據(jù)庫。首先對待檢測信號進行預(yù)處理，然后每兩個相鄰T波作為一組，先進行相關(guān)對齊，再計算交替指數(shù)，根據(jù)交替指數(shù)的判斷規(guī)則判定是否存在T波交替，并用傳統(tǒng)的譜分析法加以驗證。結(jié)果成功實現(xiàn)了短時的T波交替檢測，連續(xù)6個信號即可判斷該段信號是否存在TWA現(xiàn)象，并通過了譜分析法的交替幅度值的驗證，有更好的實時性。結(jié)論該方法可以用于短時的T波交替檢測，計算方法簡單，易于實現(xiàn)。本文還總結(jié)了影響T波交替檢測的幾個重要因素，直接計算相鄰兩T波間的交替相關(guān)指數(shù)是本文的創(chuàng)新點。
關(guān)鍵詞T波交替；相關(guān)分析法；譜分析法；心電信號

Objective T wave alternans (TWA) can forecast ventricular arrhythmias and sudden death,however,the traditional method is not real-time. This paper proposes an improved method to detect short-time TWA. Methods We enhanced the traditional correlation method to detect T wave alternans,enhancing the template for alignment and calculating the alternans index. The data sets were taken from the MIT-BIH database and the ST-T database. After data preprocessing,we regarded each two adjacent T waves as a research group. Firstly we aligned the two T waves,calculated the alternans index,then to tell whether T wave alternans existing. Results This method realized the detection of short-time TWA and may judge TWA within six adjacent signals. Spectrum analysis was proposed to verify this improved method. Conclusions This improved correlation method could be used for detecting TWA. The algorithm was simple,easy to achieve. Certain important factors influencing the detection of TWA were discussed and the innovation point of the paper was the calculation for the alternans index of the two adjacent T waves.

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