北京生物醫(yī)學(xué)工程

利用EMG運(yùn)動單位動作電位數(shù)目估算法研究痙攣型腦癱患兒神經(jīng)元發(fā)放特性_________

cerebral palsy based on the estimation of motor unit action potential number in electromyography signal

作者：姚博楊基海陳香吳德錢玲玲周逸峰

單位：           中國科學(xué)技術(shù)大學(xué)電子科學(xué)與技術(shù)系(合肥230027)    

關(guān)鍵詞：小兒腦癱；表面肌電信號；運(yùn)動單位動作電位數(shù)目估計(jì)；平滑非線性能量算子；平均發(fā)放間隔

分類號：

出版年·卷·期（頁碼）：2013·32·2（127-133）

摘要：

目的小兒腦癱患者的運(yùn)動障礙分級和康復(fù)評估具有重要的臨床價值。本文利用表面肌電信號對痙攣型腦癱患兒的運(yùn)動神經(jīng)元發(fā)放特性進(jìn)行研究，旨在為腦癱患兒的運(yùn)動障礙評估提供一種量化指標(biāo)。方法采用平滑非線性能量算子(smoothed nonlinear energy operator，SNEO)算法，對痙攣型腦癱患兒表面肌電信號中的運(yùn)動單位動作電位(motor unit action potential，MUAP)數(shù)目進(jìn)行估計(jì)，獲得MUAP的平均發(fā)放間隔(inter-pulse interval，IPI),并根據(jù)醫(yī)生采用的分級結(jié)果和健康人MUAP平均發(fā)放時限的早期研究結(jié)果進(jìn)行對比驗(yàn)證。結(jié)果對14名不同運(yùn)動障礙級別腦癱患者的實(shí)驗(yàn)結(jié)果顯示，其肌電信號MUAP的IPI與他們活動度的級別即運(yùn)動障礙的程度呈正相關(guān)的關(guān)系，且具有明顯差異。結(jié)論研究結(jié)果表明本文方法有效，采用IPI參數(shù)能夠反映腦癱患兒的運(yùn)動障礙程度。

Objective The evaluation of dyskinesia and rehabilitation for cerebral-palsy（CP）patients is of important clinical value. The firing characteristics of motor neurons in child cerebral palsy are studied by means of surface electromyography（sEMG）to provide an index for CP patients. Methods The smoothed nonlinear energy operator（SNEO）algorithm is adopted to estimate the number of motor unit action potential（MUAP）in sEMG collected from CP patients. Then，inter-pulse interval(IPI）of MUAP is achieved. The results are verified by the diagnosis and early research on mean potential duration of healthy male volunteers. Results The results of 14 patients’ sEMG signals in different CP levels show that there is a positive correlation between their IPIs and the severity of the disease，which also means the levels of CP dyskinesia，and the differences in various CP levels are significant. Conclusions Experimental results of real CP sEMG signals demonstrate that this method is effective and IPI of MUAP can be used as quantitative index for the evaluation of CP dyskinesia and rehabilitation.

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