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靜息態(tài)腦功能網(wǎng)絡(luò)分析的假設(shè)驅(qū)動和數(shù)據(jù)驅(qū)動方法綜述_________

Review of hypothesis driven and data driven methods for brain functional network analysis

作者:               杜宇慧  桂志國  劉迎軍  陳芳芳          
單位:           中北大學(xué)信息與通信工程學(xué)院(太原030051)    
關(guān)鍵詞:           腦功能網(wǎng)絡(luò);獨立成分分析;聚類;組信息;半監(jiān)督學(xué)習(xí)      
分類號:
出版年·卷·期(頁碼):2013·32·3(307-311)
摘要:

基于功能磁共振成像的研究已發(fā)現(xiàn)在腦區(qū)之間存在低頻波動一致的腦功能網(wǎng)絡(luò)。腦功能網(wǎng)絡(luò)有助于認(rèn)識腦功能和診斷神經(jīng)精神疾病,而腦功能網(wǎng)絡(luò)分析方法在其中具有重要地位。本文首先綜述了假設(shè)驅(qū)動和數(shù)據(jù)驅(qū)動進(jìn)行腦功能網(wǎng)絡(luò)分析的兩類方法,接著對常用的基于感興趣區(qū)、基于體素、基于獨立成分分析、基于主成分分析和基于聚類方法的原理、優(yōu)缺點做了詳細(xì)介紹,并著重闡述了最近提出的組信息指導(dǎo)的獨立成分分析方法,及基于半監(jiān)督學(xué)習(xí)技術(shù)的感興趣區(qū)選擇方法,最后對改進(jìn)方向進(jìn)行了展望。

The research of functional magnetic resonance imaging (fMRI) has revealed the coherent fluctuation of low frequency signals between anatomically separated brain regions,which indicates functional network. Brain functional networks help better understanding of brain function and diagnosis of mental disease,and methods for analyzing brain functional networks play an important role. The paper firstly reviews two categories of methods for functional networks analysis:hypothesis driven and data driven methods,and then presents the theory,advantages and shortcomings of the traditional methods,including region of interests (ROI) based method,voxel based method,independent component analysis (ICA),principal component analysis (PCA) and clustering method. Furthermore,the paper highlights the recently proposed group information guided ICA method and semi-supervised learning based ROI selection method. Finally,future potential improvements of the methods are prospected.

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