北京生物醫(yī)學(xué)工程

亞低溫控制實(shí)驗(yàn)裝置的設(shè)計(jì)

Design of mild hypothermia control experimental device

作者：薄雪峰趙冰洪劉慶凱曹海勇宋紅芳劉志成

單位：首都醫(yī)科大學(xué)生物醫(yī)學(xué)工程學(xué)院(北京100069)

關(guān)鍵詞：亞低溫治療；局部降溫；溫度控制；實(shí)驗(yàn)裝置

分類(lèi)號(hào)：

出版年·卷·期（頁(yè)碼）：2013·32·5（503-507）

摘要：

目的亞低溫治療作為一種輔助治療手段，可使重型顱腦創(chuàng)傷病死率下降，促進(jìn)其神經(jīng)功能恢復(fù)并改善預(yù)后。本文設(shè)計(jì)了一種可實(shí)現(xiàn)局部亞低溫控制的外圍電路實(shí)驗(yàn)裝置。方法該實(shí)驗(yàn)裝置包括單片機(jī)控制系統(tǒng)、人機(jī)交互界面、輸液泵、雙腔導(dǎo)管和傳感器。傳感器監(jiān)測(cè)目標(biāo)位置的溫度變化，單片機(jī)系統(tǒng)控制輸液泵驅(qū)動(dòng)冷卻液，在導(dǎo)管的熱交換頭處進(jìn)行熱交換，以實(shí)現(xiàn)并維持目標(biāo)位置的亞低溫狀態(tài)。結(jié)果設(shè)計(jì)并實(shí)現(xiàn)了局部亞低溫控制的外圍電路實(shí)驗(yàn)裝置，實(shí)驗(yàn)結(jié)果顯示可以較快的速率實(shí)現(xiàn)降溫效果，并通過(guò)自動(dòng)控制實(shí)驗(yàn)裝置的冷卻液速率來(lái)實(shí)現(xiàn)亞低溫的保持。結(jié)論該實(shí)驗(yàn)裝置可為局部定點(diǎn)亞低溫控制技術(shù)提供研究基礎(chǔ)。

Objective Mild hypothermia，as a kind of auxiliary therapy，decreases severe head trauma rate，promotes the nerve function recovery and improves the prognosis.We design a peripheral control circuit that can achieve mild hypothermia in local part.Methods The experimental device consists of control center，man-machine interface，infusion pump，double catheter and sensor.The temperature of the target position is inspected by the sensor.The driven cooling fluid of infusion pump is controlled by the SCM system.Heat exchange takes place between the head heat exchanger and the simulated body organization to achieve and maintain the state of mild hypothermia in the target position.Results We design and implement a peripheral control circuit that can achieve mild hypothermia in local part.The effect of mild hypothermia is proved and the state of mild hypothermia in the target position maintains through controlling the speed of the cooling fluid.Conclusions The experimental device provides a research foundation for local mild hypothermia.

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