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一種新型輸尿管支架管及磁性導(dǎo)尿管

A novel ureteral stent and the magnetic catheter

作者: 王瑨  黃赤兵  馮嘉瑜  胡文剛  許曉婷  宋亞軍  孫幀  陳益榮  王平賢  范明齊                  
單位:                      第三軍醫(yī)大學(xué)新橋醫(yī)院(重慶400037)        
關(guān)鍵詞:                     輸尿管支架管;磁性;拔除           
分類號:
出版年·卷·期(頁碼):2014·33·2(179-184)
摘要:

目的 設(shè)計一種末端帶有可釋放型納米鐵牽引線的新型輸尿管支架管及磁性拔除導(dǎo)尿管,并初步評估這種新型拔管方法的可行性。方法 設(shè)計并制備新型輸尿管支架管及磁性拔除導(dǎo)尿管,并對部件和材料進行性能測試,包括熱失重分析測定納米鐵牽引線的鐵含量、機械牽伸實驗測定納米鐵牽引線斷裂強度、磁強計測定導(dǎo)尿管磁性強度并檢測磁性導(dǎo)尿管夾持力大小,以及新型輸尿管拔除方法有效性檢驗,即在前期研制的透明泌尿系統(tǒng)模擬模型中進行拔除實驗,統(tǒng)計拔除成功率及拔除阻力。結(jié)果 單位長度牽引線中納米鐵粉的質(zhì)量分?jǐn)?shù)約為23%,牽引線斷裂強度為10.12 N,磁性導(dǎo)尿管磁性強度578 emu/g,磁性導(dǎo)尿管夾持力(10.79±0.84) N。新型輸尿管支架管拔除成功率98%,拔除過程中最大阻力為(5.26± 0.53) N。結(jié)論 這種新型拔管方法有效可行,且現(xiàn)有材料能夠完成制作。該新型輸尿管支架管及磁性拔除導(dǎo)尿管提供了一種微創(chuàng)的、不需影像學(xué)引導(dǎo)即可進行拔管的方法,具有良好的應(yīng)用前景。

Objective To design a novel ureteral stent with a nanoscale iron traction thread at the end and the magnetic catheter,and to assess the feasibility of the innovative removal method.Methods We designed and manufactured the stent and catheter.We tested the properties of them,including:nanoscale iron powder content test of the traction thread by thermo-gravimetric analysis,breaking strength test of the traction thread by tractor,magnetization identification of the magnetic catheter by magnetometer,and magnetic catheter clamping force test.We confirmed the validity of the new removal method through conducting removal experiments in a transparent model of urinary system,which was generated in early study,and calculated success rate and removal resistance.Results The mass fraction of nanoscale iron powder was 23% in the dacron traction thread,the breaking strength of the dacron traction thread was 10.12 N,the magnetization of the magnetic catheter was 578 emu/g,and magnetic catheter clamping force was(10.79±0.84) N.Removal experiments were carried out 50 times,the success rate was 98%,and the mean maximum resistance of removal was(5.26± 0.53) N.Conclusions This study preliminarily confirmed that the innovative removal method was effective,and could be manufactured by existing materials.This offered a minimally invasive method to remove the ureteral stent without image guide.The novel ureteral stent and the magnetic catheter had a bright prospect.

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