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便攜式聽覺穩(wěn)態(tài)誘發(fā)響應(yīng)聲音刺激器設(shè)計

Portable stimuli generator for auditory steady state responses

作者: 鄭璞潔  應(yīng)俊  高小榕                  
單位:                      清華大學醫(yī)學院生物醫(yī)學工程系(北京100084)        
關(guān)鍵詞:                     聽覺穩(wěn)態(tài)誘發(fā)響應(yīng);  聽覺刺激器          
分類號:
出版年·卷·期(頁碼):2014·33·4(331-336)
摘要:

目的 聽覺穩(wěn)態(tài)誘發(fā)響應(yīng)(auditory steady state response, ASSR)對大腦的聽覺系統(tǒng)研究有重要意義,但傳統(tǒng)的用于ASSR實驗的刺激設(shè)備較為昂貴且使用不便,本文給出一種便攜式聽覺刺激器的設(shè)計方案。方法 以TI的TMS320C5515芯片作為核心處理器,利用SD卡存儲用于聲音刺激的配置文件以及聲音數(shù)據(jù),通過主芯片提供的SD卡接口及DMA通道讀取聲音數(shù)據(jù),然后經(jīng)過I2S總線,傳遞數(shù)據(jù)至音頻編解碼器中,最后完成聲音的播放。該系統(tǒng)提供可視化的界面,供用戶選擇配置文件。同時提供一個基于MATLAB的工具包,用于將普通的音樂格式轉(zhuǎn)化為系統(tǒng)兼容的聲音數(shù)據(jù)格式。結(jié)果 本系統(tǒng)支持8~192kHz的聲音采樣率,支持單聲道和立體聲,支持聲音位寬包括16位和32位,且允許輸出聲壓級在87.5dB的動態(tài)范圍內(nèi)變化,變化的步長為 0.5dB。為驗證本系統(tǒng)的實用性,4個受試參與了一系列ASSR實驗,獲得了預(yù)期的實驗結(jié)果。結(jié)論 本系統(tǒng)可用于ASSR實驗中,且系統(tǒng)可保證長時間穩(wěn)定頻率的聲音輸出,因系統(tǒng)功耗小于200mW,如果使用1000mA·h的3.7V的鋰電池供電,則系統(tǒng)可持續(xù)工作超過18.5h。

Objective The research for auditory steady state response (ASSR) is important for understanding the auditory system in human brain.Unfortunately, the devices for generating the auditory stimuli in previous research are expensive yet inconvenient.This paper proposes a novel portable auditory stimuli generator for ASSR experiments.Methods The main processor of this system is TI’s TMS320C5515 digital signal processor (DSP).A SD card is used to store configuration files and sound files which specify the sound stimuli.The main processor reads data from the SD card through the SD interface and the DMA channel.Then, the data are transmitted from the processor to an audio coder and decoder (CODEC) through the I2S bus and finally achieves the sound playing.A graphic user interface is provided for the user to choose the configuration file.Moreover, a toolbox based on MATLAB is offered to translate the common music formats into the compatible sound format.Results The permissible sampling rates for playback range from 8kHz to 192kHz.The channels can be either mono or stereo, and the data resolution can be 16bits or 32bits.The playback volume can be adjusted in 87.5dB’s range, and the step for adjustment is 0.5dB.A series of ASSR experiments have been conducted on 4 subjects to demonstrate the feasibility of this system.Conclusions This system can be used successfully in the ASSR experiments to provide long-term and stable sound outputs.The system holds a power-consumption less than 200mW.With a 1000mA·h and 3.7V’s lithium battery, this system can keep on working for more than 18.5h.

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