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Objective In order to receive and store the image information transmitted by wireless capsule endoscope, a data receiving and storing system based on CF card outside human body is introduced in this paper. Methods By utilizing the structure of ‘CPLD+FIFO+MCU’, this system synchronizes the analog image frames received, control the conversion of A/D and save the result in FIFO under the control of CPLD. And during the hibernation, MCU in the system reads the cache data and stores it into CF by the format of FAT32 file system, which is convenient for the further image data decode. Results The designed system receives and stores the transmitted signal successfully and a clear and complete image is achieved in the experiment in vitro. Conclusions The designed system is compact and portable and has certain application value in the burst signal sampling and storing.