北京生物醫(yī)學(xué)工程

基于形態(tài)學(xué)重構(gòu)的宮腔鏡下子宮內(nèi)膜腺體開口標(biāo)記算法

Marking algorithm of endometrial glandular openings based on morphological reconstruction under hysteroscopy

作者：楊淼黃曉武閔樂泉姚紅串

單位：                                 首都醫(yī)科大學(xué)生物醫(yī)學(xué)工程學(xué)院（北京100069）            

關(guān)鍵詞：宮腔鏡;子宮內(nèi)膜腺體開口;形態(tài)學(xué)重構(gòu);多尺度高斯濾波器

分類號(hào)：

出版年·卷·期（頁(yè)碼）：2015·34·5（468-471）

摘要：

目的在宮腔鏡下為胚胎種植窗口期的子宮容受性提供一個(gè)量化的評(píng)價(jià)方法，提

出一個(gè)宮腔鏡下的子宮內(nèi)膜腺體開口標(biāo)記算法。方法采用數(shù)學(xué)形態(tài)學(xué)重構(gòu)算法

提取可能的腺體開口區(qū)域，利用多尺度的高斯濾波增強(qiáng)腺體區(qū)域去除噪聲，最

后使用數(shù)學(xué)形態(tài)學(xué)的區(qū)域最大值標(biāo)記腺體開口。結(jié)果該標(biāo)記算法的標(biāo)記結(jié)果與

專家標(biāo)記結(jié)果進(jìn)行比對(duì)，靈敏度為84.72%±8.00%，Dice相似度系數(shù)達(dá)83.80%±

4.56%。結(jié)論經(jīng)仿真和真實(shí)數(shù)據(jù)驗(yàn)證，提出的子宮內(nèi)膜腺體開口標(biāo)記算法是有

效的。

Objective To provide a quantitative evaluation method of the window

of uterine receptivity for implantation, a marking algorithm of

endometrial glandular openings under hysteroscopy was proposed.

Methods Candidate areas of glandular openings were detected by

morphological reconstruction algorithm and enhanced by multi-scale

Gaussian filter, while noises were suppressed. The glandular openings

were finally marked based on the regional maximum value. Results The

result of the proposed algorithm was compared with the result of the

experts. The sensitivity of the proposed algorithm was 84.72% ±

8.00%, Dice similarity coefficient reached 83.80% ± 4.56%.

Conclusions Simulation and experiment results indicated that the

proposed algorithm could effectively mark the endometrial glandular

openings under hysteroscopy.

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