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___________基于EEG的酒精依賴(lài)對(duì)腦功能的影響_________ Influences of alcohol dependence on brain function based on EEG |
| 作者： 李寧 邢麗冬 錢(qián)志余 張璽 鄧建輝 何俊豪 于婷婷 |
| 單位： 南京航空航天大學(xué)自動(dòng)化學(xué)院生物醫(yī)學(xué)工程系(南京210016)<p></p> |
| 關(guān)鍵詞： 腦電信號(hào)；酒精依賴(lài)；重心頻率；R值 |
| 分類(lèi)號(hào)： R318.04 |
| 出版年·卷·期（頁(yè)碼）：2015·34·6（568-572） |
| 摘要： |
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目的 研究酒精依賴(lài)對(duì)個(gè)體腦電信號(hào)的影響,以期了解酒精依賴(lài)對(duì)個(gè)體健康的影響。方法 基于亨利（ 紐約州立大學(xué)）實(shí)驗(yàn)所得的102例腦電數(shù)據(jù)，對(duì)數(shù)據(jù)進(jìn)行預(yù)處理，去除偽跡，提取腦電特征波并計(jì)算包含 功率譜、R值和重心頻率在內(nèi)的腦電參數(shù)，進(jìn)行統(tǒng)計(jì)學(xué)分析，以討論分析酒精依賴(lài)患者與健康人的腦電差 異。結(jié)果 相對(duì)于健康人，酒精依賴(lài)患者的腦電中α波相對(duì)功率減小，其中以頂區(qū)和枕區(qū)最為顯著。θ波 功率減小，在顳葉的變化較為明顯。β波相對(duì)功率在各個(gè)腦區(qū)均大幅提高。全腦區(qū)R值均減小，重心頻率 均增大。結(jié)論 相對(duì)于健康人群，酒精依賴(lài)患者的腦電信號(hào)普遍向高頻遷移，表明酒精依賴(lài)可以使大腦皮 質(zhì)的興奮度增強(qiáng)，腦活動(dòng)更為復(fù)雜。 |
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Objective Aiming at studying the influences of alcohol dependence on individual brain electric signals,we made a comparison between the patients with alcohol dependence and the healthy control subjects,expecting to get the impact of alcohol on individuals.Methods One hundred and two cases of EEG data used in this paper were from Henry’s experiment in State University of New York.After removing the artifact,extracting the EEG feature waves and calculating the relevant EEG parameters,the statistics analysis was done to analyze the difference of EEG between alcoholics and healthy control subjects.Results Compared with healthy control subjects,the alcoholics’ relative power of α band decreased,especially in parietal and occipital regions.The power of θ band decreased,especially in temporal region.The power of β band increased in all brain regions.The R-value decreased while the gravity frequency increased in each region.Conclusions Alcohol dependence makes patients’ EEG signals migrates to the high frequency,increases the excitability of cerebral cortex and makes brain activities more complicated. |
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地址：北京安定門(mén)外安貞醫(yī)院內(nèi)北京生物醫(yī)學(xué)工程編輯部 電話：010-64456508 傳真：010-64456661 電子郵箱：[email protected] |