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個性化肝癌患者肝臟相關(guān)動脈血管的三維容積重建及其應(yīng)用

Three-dimensional volume reconstruction of hepatic arteries for individual HCC patients and its application

作者: 丁金立  李宏軍  張巖巖  張琦  夏振營  趙夕  劉有軍 
單位:首都醫(yī)科大學(xué)附屬北京佑安醫(yī)院放射科<p>(北京100069)</p><p></p>
關(guān)鍵詞: 三維容積重建;肝動脈血管;肝癌;CT;個性化 
分類號:R318.04
出版年·卷·期(頁碼):2016·35·6(620-625)
摘要:

目的 對個性化肝癌患者肝臟周圍的動脈血管進(jìn)行三維容積重建,并探討其潛在的臨床及科研應(yīng)用。方法 針對個性化肝癌患者,通過GE Lightspeed 64排螺旋CT進(jìn)行掃描,基于300層腹部連續(xù)斷層圖像,利用Minics進(jìn)行三維圖像的容積重建,獲取肝臟周圍動脈血管的三維結(jié)構(gòu),結(jié)合臨床探討其在疾病診療和科研方面的指導(dǎo)作用。結(jié)果 利用三維容積重建得到了局部腹腔干、肝動脈、肝固有動脈、胃左動脈等血管的三維容積模型。其中,腹腔干血管直徑在12.7~18.6mm之間,肝動脈血管直徑約為5.3mm、肝固有動脈血管直徑約為4.5mm、胃左動脈血管直徑約為4.6mm。結(jié)論 利用三維容積重建技術(shù)所得的肝臟周圍血管模型提供了較二維圖像更直觀的解剖顯示和較好的后處理優(yōu)勢,是個性化有限元模型的基礎(chǔ),為肝動脈血流的有限元分析提供了數(shù)學(xué)模型,對制定更合理的肝臟外科手術(shù)方案及術(shù)后評價具有一定的指導(dǎo)意義。

Objective To carry out the three-dimensional volume reconstruction of hepatic arteries for an individual hepatic cellular cancer (HCC) patient, and discuss its potentials in clinical and research applications. Methods GE Lightspeed 64 multi-detector helical CT was used for patient examination, from which 300 slices were employed for three-dimensional volume reconstruction by utilizing the commercial software Minics, and for further discussion of its potential applications. Results A three-dimensional model including partial celiac axis (about 12.7-18.6mm), hepatic artery (about 5.3mm), proper hepatic artery (about 4.5mm) and left gastric artery (about 4.6mm) were reconstructed via the three-dimensional volume reconstruction. Conclusions The three-dimensional model reconstructed by the volume reconstruction provides a more visual display than the original CT images, and has better post-processing advantages. The reconstructed model is the base of finite element model and provides a better mathematical model for future hemodynamic simulations of hepatic arteries, which is helpful for appropriate liver surgery and post-surgical evaluations.


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